Author Login IJIRT Partner Network (IPN) Login

Different strategies, approaches and recent advances in transcellular brain drug delivery.

  • Unique Paper ID: 150208
  • Volume: 7
  • Issue: 4
  • PageNo: 95-103
  • Abstract:
  • There are three types of barrier present in central nervous system such as Blood Brain Barrier, Blood Cerebro-Spinal Fluid Barrier, and Blood–Arachnoid Barrier. BBB is the very tough barrier for the transport of drugs to brain. For the treatment of various diseases related to CNS like brain cancer, Alzheimer disease, parkinson’s disease, epilepsy, psychiatric disorders or neurodegenerative diseases, different types of drugs are available. But they have some lacuna for transport of drug though these barriers and reaching drug to the target site. This review is one of the attempts to amend the recent information on cellular structure of BBB as well as different procedures planned to cross it. Different strategies and approaches are utilized to improve brain targeted drug delivery system. Lipophilicity of drug can be increased by chemical modification, while colloidal carriers like Nanoparticles, Dendrimers, Lipososmes , Nanogels enhances properties and therapeutic effect of drug in brain. Using these strategies, tumour targeting nanoparticles are developed according to the EPR. This effect could be useful to brain diseases by considering the leaky BBB. Information on structure and function of brain, recent strategies to deliver drugs into brain for treatment of CNS diseases are involved in this article.
email to a friend

Cite This Article

  • ISSN: 2349-6002
  • Volume: 7
  • Issue: 4
  • PageNo: 95-103

Different strategies, approaches and recent advances in transcellular brain drug delivery.

Related Articles

22 Nov, 2021

PREPARATION AND STANDARDIZATION OF EGG SHELL BHASMA

Read More
Impact Factor
8.01 (Year 2024)
UGC Approved
Journal no 47859

Join Our IPN

IJIRT Partner Network

Submit your research paper and those of your network (friends, colleagues, or peers) through your IPN account, and receive 800 INR for each paper that gets published.

Join Now

Latest Publication

Archive

View More

Recent Conferences

NCSEM 2024

National Conference on Sustainable Engineering and Management - 2024 Last Date: 15th March 2024

Submit inquiry