• ISSN: 2349-6002
  • UGC Approved Journal No 47859

Crystal structure of 4-(4-Bromo-phenoxymethyl)-5, 7-dimethyl-chromen-2-one (C18 H15 Br O3)

  • Unique Paper ID: 152611
  • Volume: 7
  • Issue: 4
  • PageNo: 383-386
  • Abstract:
  • 4-Phenoxymethylcoumarin was reported by by the reaction of 4-bromomethylcoumarin with phenol. Compound was subjected to the Claisen rearrangement at high temperature, which gave negative results Subsequently a number of 4-aryloxymethylcoumarins were synthesised as possible anti-microbial agents Introduction of biocompatible fragments like vanillin and paracetamol resulted in novel 4-aryloxymethylcoumarins and which exhibited anti-inflammatory, analgesic and interesting photophysical properties also. The first report on the X-ray diffraction studies on 4-aryloxymethylcoumarins has revealed that the molecules exist as head-tail dimers in solid state as observed in the case of 7-methyl-4-tolyloxymethylcoumarin In the light of above observations following 4-aryloxymethylcoumarins possessing chloro/bromo substituents have been subjected to X-ray diffraction studies.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 7
  • Issue: 4
  • PageNo: 383-386

Crystal structure of 4-(4-Bromo-phenoxymethyl)-5, 7-dimethyl-chromen-2-one (C18 H15 Br O3)

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UGC Approved
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